The 30-year-old is due to start running at the end of the month and hopes to return in time for the next Clasico at Camp Nou
The Spaniard sustained a broken leg in the Club World Cup in December and has since been engaged in a race to regain fitness in time for his country's defence of their European Championship crown.
The 30-year-old recently confirmed that he was on course for a rapid recovery from the injury and could be back in action in as little as two months.
Villa is working on the injury six hours per day and is cycling, swimming and undergoing electrotherapy to speed up his recovery.
He is soon to start work using an anti-gravity treadmill, which allows him to run without undue impact on his joints.
Should all go to plan, the former Valencia man will start running at the end of February, before strengthening his muscles in March.
Barcelona will welcome Real Madrid to Camp Nou on April 22.
Since November, Goal.com has been publishing exclusive extracts from Graham Hunter's highly-anticipated new book, 'Barca: The Making of the Greatest Team in the World'. The very last extract, which is published on Friday, looks at Andres Iniesta's risky return from injury in the 2009 Champions League Final and how he was described by Wayne Rooney as the 'best midfielder in the world'. Don't miss it!