The Argentine believes Jose Mourinho's men are a long way ahead of their local rivals, while voicing his fear that Xabi Alonso could miss the Clasico through suspension
Jose Mourinho's side are currently 15 points ahead of the Colchoneros and, speaking to Marca, the 56-year-old was confident his old employers would come out on top.
"Atletico are full of doubt and Madrid are full of conviction; the feeling is that Madrid can win with ease," Valdano stated.
The Argentine went on to voice his concern that Xabi Alonso could pick up a suspension, having already accumulated four yellow cards this season.
"There's a chance we'll lose him against Barcelona [on December 10]. After [Cristiano] Ronaldo, he is the most important player in the squad," he explained.
Real Madrid currently sit three points clear at the top of the table, but the former sporting director believes the team cannot be judged until they lock horns with the Catalans.
"It takes a peak from every individual. Also, the team collectively gives the impression of confidence. The unit of measurement will be against Barcelona."
Starting last week and continuing every Friday through to January, Goal.com will publish extracts from Graham Hunter's highly-anticipated book, Barca: The Making of the Greatest Team in the World. This Friday, tune in for a new enthralling extract on how Joan Laporta and Sandro Rosell used David Beckham as a vote-winner in the club elections of 2003, even though a deal was already done between Manchester United and Real Madrid. Don't miss it!