The coach of the Vicente Calderon outfit is an admirer of the 25-year-old's skills, and labelled him a great signing for his side
The Colombia international joined Atletico from Porto in the summer in a deal worth €40 million as the club were on the lookout for a replacement for Sergio Aguero.
After an indifferent debut against Valencia, Falcao has been hot in front of goal, scoring six times in the last three games.
As he watched Falcao score a brace in Wednesday's 4-0 win over Sporting Gijon in La Liga, Manzano confessed he is in awe with the striker's qualities.
"It never ceases to amaze that Falcao has adapted so quickly to the team and started scoring goals this way," Manzano is quoted by AS as saying.
"But even more important than the goals is his humility. He is a great person who has been a great fit in the dressing room.
"No doubt that we have signed a magnificent striker who will be on par with the great No.9s in Spain, like Lionel Messi or Cristiano Ronaldo.
"It was really hard to land him and it was a great signing."
Atletico are currently eighth in the league, with seven points from four games, and will visit Barcelona at the weekend.