The German wonderkid will again be held back from the beginning of the match, however Klopp hopes he will get more game time than in the previous fixture against Werder Bremen.
The 20-year-old featured in his side's Bundesliga opener, scoring the winning goal in their 2-1 victory over Werder Bremen, however this hasn't guaranteed him a place in Jurgen Klopp's starting line-up.
Gotze will hope to have the same impact this weekend, as he looks to prove himself worthy of being a prominent figure in his manager's first team plans.
"Mario is a very strong player and has trained very well this week. If possible, he will play longer than in the match against Bremen." explained the Dortmund coach, speaking to Bild.
After niggling injuries to his hip, which hindered his progress last season, Gotze will hope to gain a regular place in Dortmund's side this campaign as they aim to retain the Bundesliga title.
"I'm 100 percent fit. I will display it. I hope that I get more confidence from the coach." stated Gotze.