The 26-year-old Galatasaray goalkeeper revealed his hopes of a move to England, with the Red Devils reportedly interested as doubts remain over David de Gea and Anders Lindegaard
The 26-year old impressed during his team's 1-0 defeat to the Red Devils in the Champions League earlier this season, making a number of vital saves including a penalty stop from Nani.
And with Sir Alex Ferguson reportedly interested in the Uruguay international as doubts remain over both David de Gea and Anders Lindegaard, Muslera admits he is looking for a "step forward" in his career.
"The Premier League is my childhood dream," he told Haberturk. "I always want to move forward in football. I started off with Wanderers, then Nacional, then Lazio and then, a step forward, Galatasaray.
"[It's] because i've always wanted to play for a club that participates in the Champions League."
Galatasaray sit top of the Turkish Super Lig by three points, but Muslera believes a transfer to a top English club is what the majority of players around the globe aim for - and he is certainly open to a deal.
"It's probably any footballer's dream to play in England, not just mine. I have a contract with Galatasaray but if an offer comes through and it benefits the club, then why not?"
Galatasaray vice-president Ali Durust stated after the defeat to United that the club "never want to sell" Muslera, who was voted sixth-best goalkeeper in the world in 2011 by the International Federation of Football History & Statistics.
De Gea is currently Ferguson's first-chice goalkeeper, but the No.1 jersey has been traded numerous times this season, with neither him nor Lindegaard making a convincing case to be considered an indisputable pick.