The Croatia international moves to Germany on a temporary basis after struggling for first-team football this term, making just one start in the Premier League since the summer
This season the Croatia international has made just three league appearances for Spurs and one start, a significant difference from his first season in London when he was a first-team regular.
"With this signing, we provide ourselves with a high-quality alternative. Vedran Corluka is a seasoned professional who can give our team an immediate quality boost," Leverkusen CEO Wolfgang Holzhauser told his club's official website.
The Dinamo Zagreb youth product moves to the BanArena initially on loan until the end of the current campaign. However, Goal.com understands Robin Dutt's side have the option to sign the defender permanently in the summer.
"He can be used not only on the right side, but also in the centre or at left-back. We are very pleased that we were able to realise his transfer," added Leverkusen sporting director Rudi Voller.
Since joining Spurs from City in 2008, Corluka has made 107 appearances. He joins a Leverkusen side looking to close the ten-point gap between themselves and the three teams who currently top the Bundesliga - Bayern Munich, Borussia Dortmund and Schalke.