Cassano joined the Marassi outfit on loan from Real Madrid in 2007 and the move was made permanent for free last summer, provided Samp pay los Merengues €5 million if the fantasista moves on in the next three years.
The former Bari youngster is tied to the Ligurians until 2013, but he has an escape clause of €18m in his contract.
It is suggested that Inter and Samp are already in advanced negotiations over a fee. David Suazo and midfielder Luis Jimenez could be part of the deal and could move to Genova in part-exchange.
Meanwhile, Twente hitman Marko Arnautovic will land in Milan today to undergo a medical and pen his new contract with the Beneamata.
Vince Masiello, Goal.com