The Dutch maestro was a doubt before the match, but he has passed a late fitness test and starts for Leonardo's men, whilst Hernandez is preferred to Pinilla for the Rosanero
The Dutchman has been absent in recent weeks for the Nerazzurri, after picking up a knock in a training session and consequently he has missed his side's end of the season run-in.
However, he has made the grade after being declared fit, much to the delight of his coach Leonardo, who will be hoping the 26-year old can help inspire his team to glory in the Coppa Italia.
As a result of his inclusion, Houssine Kharja is demoted to the bench. Yuto Nagatomo retains his place at right-back, as Maicon remains suspended.
Meanwhile for Palermo, they line up with a generally predictable team, in what will be their first Coppa Italia final appearance since 1979.
The only call made by Delio Rossi comes in attack, as Uruguayan forward Abel Hernandez is preferred to Mauricio Pinilla, who has been linked to their opponents in the past week.
There were whispers that Fabio Liverani may start in midfield for Palermo, but Afriyie Acquah has passed a late fitness test and retains his place in the centre of his side's midfield.
Inter starting XI: Julio Cesar; Nagatomo, Lucio, Ranocchia, Chivu; Zanetti, Thiago Motta, Stankovic; Sneijder; Pazzini, Eto'o.
Subs: Castellazzi, Kharja, Mariga, Milito, Materazzi, Samuel, Pandev.
Palermo starting XI: Sirigu; Cassani, Munoz, Goian, Balzaretti; Migliaccio, Acquah, Nocerino; Ilicic, Pastore; Hernandez.
Subs: Benussi, Kasami, Miccoli, Liverani, Darmian, Pinilla, Carrozzieri.