The 51-year-old is adopting a long-term view ahead of his side's Derby d'Italia showdown and says a single result will not dictate their form in the months ahead
Last season the Nerazzurri were unable to maintain their form after a 3-1 victory at Juventus stadium, winning just three of their 12 league games that followed.
Mazzarri is hoping to avoid a similar fate this year, as he prepares to take charge of his first ever Derby d’Italia after succeeding Andrea Stramaccioni over the summer.
"You can’t judge a team based on a single game," the 51-year-old told reporters.
"That match from last year is a case in point: you have to make sure that winning one game is not an end in itself.
"We’re not looking at this one match but rather at being consistent."
The former Napoli boss did not have as much time to prepare his team as he would have liked this week, with many players returning from international duty as late as Thursday evening.
"I’ll do what I can to give my players all the input possible so that they can perform well.
"The last few players came back yesterday and I didn’t have time to talk to them with the focus needed. I told them to rest up as best they could so that they could concentrate today and take in everything I have to say."
Mazzarri also commented on Juventus and identified their strength in depth as the secret behind their success over the course of the last two seasons.
"They’re strong all around, from the goalkeeper right through to the centre forward," he added.
"I wouldn’t know [which one player] to focus on. It’s the team that changes the game. You don’t get very far by relying on individuals."