The Old Lady's 49-match unbeaten run was ended by their bitter rivals in November, a fact not forgotten by the Bianconeri captain
Having gone the entirety of the previous Serie A campaign unbeaten, the Old Lady maintained their invincible league form at the beginning of 2012-13, but the Nerazzurri halted their 49-match run with a 3-1 victory in November.
But while the goalkeeper admits the loss left a sour taste in his mouth, he believes it will have provided Juve with enough motivation - other than their ambitions of sealing successive titles - to overcome Andrea Stramaccioni's side.
"In the first match, Inter deserved the win, and when you lose it rightly bugs you. We have the utmost desire for revenge," Buffon told Sky Sport Italia.
Kick-off in Milan is scheduled for 14:00CET, and you can follow the match LIVE on Goal.com.