The Italy international picked up an ankle injury in the game against Juventus, and the full extent of the problem, and how long he will be out for, is not yet known
The Italy international sustained an ankle injury in the high-scoring encounter, and was forced to leave the pitch after 50 minutes of play.
Milan have announced that Abate will undergo further examination on Tuesday to determine how bad the problem is, but it remains to be seen whether the Italy international will be fully match fit in time for the Rossoneri's Serie A opener against Sampdoria.
The San Siro side take on newly promoted Samp on Sunday.
Abate, 25, has developed into an important first-team member at Milan in the past few seasons. He made 29 Serie A appearances in 2011-12.