The Uruguayan's future has been the subject of conjecture throughout the summer, but the Partenopei chief is adamant that he is going nowhere, at least not cheaply
The Uruguayan's future at the club was cast into doubt when the 63-year-old supremo proclaimed on Thursday that he would be happy to drop his star striker if he were to demand a pay rise.
However, De Laurentiis has now moved to end any speculation concerning the 25-year-old's future, stating that any interested parties would have to stump up a world-record fee for his services.
"Cavani is not for sale, but we could let him go for €100m," he told Sky Sport Italia. "This is not his actual value, but his value to me and he won't leave for less."
De Laurentiis went on to reveal that a move for Palermo left-back Federico Balzaretti is looking more and more unlikely.
"There are two problems outside of Palermo," he explained. "First, his agent is never clear and sincere, but, above all, his child and his wife, who works in Paris.
"He was clear that he wants either Palermo or Paris Saint-Germain and I respect his reasoning. If he wants to come, we will welcome him with open arms. If he doesn't, we will bring in a youngster.
"PSG cannot go around signing everyone."
The French club have, however, bought Ezequiel Lavezzi from the Partenopei this summer, as well as AC Milan duo Thiago Silva and Zlatan Ibrahimovic.