The forward showered the highest praise possible on the Portuguese trainer who he won the treble with in 2010, and spoke highly of Athletic Bilbao's Marcelo Bielsa
The 32-year-old was snapped up by the current Real Madrid boss prior to the 2009-2010 campaign from Genoa, and played an integral role in helping the Nerazzurri win Serie A, the Coppa Italia and the Champions League in the season that followed.
"Mourinho is the best coach I've ever worked under, he gave me the most extraordinary memories," Milito told Corriere dello Sport.
However, he was then quizzed on whether Marcelo Bielsa would be a worthwhile appointment for next term, and he spoke positively of the Athletic Bilbao coach, comparing him with his former mentor Mourinho.
"Given that every coach has his own methods, [Mou and Bielsa] are similar in the way they bring the group together and protect the team," he continued.
"Bielsa is a great coach and he has proved it everywhere he's been. I'm happy for him because he deserves the results he is getting."
Meanwhile, Milito is eagerly anticipating Sunday's Serie A encounter against Juventus in Turin, and is desperate to score his first-ever goal against the Coppa Italia finalists.
The hitman has spent six years in total in Serie A, including a two-year spell from 2003 until 2005 before moving to La Liga, but he has never been able to find the net against Juventus during his time in Italy.
"Winning against Juventus? We are all highly motivated to do just that. It would be a huge morale boost if we are successful on Sunday," Milito stated.
"I have never scored against Juventus so far, and I will do my utmost to end this streak in Sunday's encounter."
Milito has scored 14 goals in 23 Serie A appearances so far in 2011-12.
Sunday's match between Juventus and Inter in Turin kicks off at 20.45CET.