The midfielder is recalled to the starting lineup after being dropped for last week's clash with Atalanta, while the Giallorossi captain is back after one-game banRoma welcome back Daniele De Rossi and Francesco Totti for their eagerly-awaited derby with Lazio.
De Rossi is recalled to the midfield after being dropped for disciplinary reasons against Atalanta last weekend, while Totti returns in the trequartista role after missing the trip to Bergamo through suspension and then recovering from a foot injury sustained in training on Wednesday.
Pablo Osvaldo, Fernando Gago and Marco Cassetti all miss the game through suspension.
As for Lazio, they are without a plethora of players through injury but the Biancocelesti are buoyed by the return of midfielder Matuzalem and defender Andre Dias after their respective ailments.
In a further boost for under-pressure coach Edy Reja, Alvaro Gonzalez has recovered from a calf problem and will start alongside Hernanes and Stefano Mauri in behind lone striker Miroslav Klose.
Roma (4-3-1-2): Stekelenburg; Taddei, Juan, Heinze, Jose Angel; Simplicio, De Rossi, Pjanic; Totti; Lamela, Borini.
Lazio (4-2-3-1): Marchetti; Scaloni, Biava, Dias, Garrido; Ledesma, Matuzalem; Gonzalez, Hernanes, Mauri; Klose.
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