The Brazilian goalkeeper is back between the sticks for Claudio Ranieri's men while Jonathan makes a rare start at right-back
The side currently have Maicon, Lucio and Yuto Nagatomo all out injured so a rare start his handed to Jonathan at right-back while Javier Zanetti starts the game on the opposite flank.
There is also a recall for Giampaolo Pazzini who will partner Mauro Zarate upfront with Diego Milito haing to settle for a place on the substitute's bench.
Inter's last game before the international break was supposed to be against Genoa yet the fixture was postponed.
Claudio Ranieri will be hoping his team can pick up only their third league win of the campaign versus a mid-table Cagliari side.
Inter (4-3-1-2): Julio Cesar; Jonathan, Ranocchia, Samuel, Zanetti; Cambiasso, Thiago Motta, Stankovic; Sneijder; Pazzini, Zarate.
Subs: Castellazi, Cordoba, Faraoni, Poli, Obi, Coutinho, Milito.
Cagliari (4-3-1-2): Agazzi; Pisano, Canini, Ariaudo, Agostini; Biondini, Nainggolan, Conti; Ekdal; Nene, Thiago Ribeiro
Subs: Avarmov, Gozzi, Larrivey, Ibarbo, Perico, Rui, Ceppellini.