The former Roma tactician has underlined the club's significant ambitions for the current season as his side prepare to welcome a possible rival for domestic silverware
Serie A action resumes for the Milanese side this weekend following a good week in the Champions League, in which they beat CSKA Moscow 3-2. Napoli are no slouches having themselves won 2-0 against Villarreal in the same competition.
Ranieri feels the big game at San Siro could have an impact on how the season turns out for president Massimo Moratti's club.
"This is a Scudetto clash. Napoli have improved, they are doing great things in the Champions League and they showed a winning mentality in Europe," he explained during a press conference on Friday.
"In terms of Inter, I feel we are a title-winning team even if our position in the league suggests otherwise.
"But, I am convinced the game against Napoli will be one for the title.
"We want to win because winning is good for the team. If Inter were feeling sick, then we need to keep taking medicine by winning."
Kick-off is at 20:45 (CET) and Inter are currently 16th in the league, while Napoli sit in fourth, one point behind joint-leaders Juventus and Udinese.
Meanwhile, the latest news from Italy is that Inter striker Diego Milito has a calf problem, but he remains part of the matchday squad.