The front two get another run-out as the champions continue to line up without the injured Zlatan Ibrahimovic and Robinho, while injuries elsewhere continue to hamper them
The pairing start together once more in the continued absence of Zlatan Ibrahimovic and Robinho, with Milan eager to bounce back after Sunday night's 3-1 defeat to Napoli at the San Paolo.
The unbeaten visitors show no major surprises in their line-up, with leading marksman Antonio Di Natale looking to add to his four goals in all competitions this term.
The clash kicks off at 20:45 (CET), with the Friuli side certain to remain ahead of their hosts whatever the result.
AC Milan (4-3-1-2): Abbiati; Abate, Nesta, Thiago Silva, Zambrotta; Nocerino, Van Bommel, Seedorf; Aquilani; Pato, Cassano.
Udinese (3-5-1-1): Handanovic; Benatia, Danilo, Domizzi; Basta, Isla, Badu, Asamoah, Armero; Torje; Di Natale.