Following wins over Macedonia and Croatia, Gordan Strachan will be hoping that his squad can use that momentum to triumph in three consecutive games for the first time since 2007
Landon Donovan scored a hat-trick as the Americans ran riot in a 5-1 victory in Jacksonville in May 2012.
Gordon Strachan has since taken over as Scotland boss and midfielder Barry Bannan is confident that they will give a better account of themselves, after securing back-to-back wins over Macedonia and Croatia to finish their World Cup qualifying campaign on a high note.
"It was a freak night the last time we played [USA]," he told the press. "I think they scored straight away. They were good, but we were poor that night. We had a lot of call-offs. They were flying. It was tough.
"Hopefully, this week, we can get our own back. This time we have finished our World Cup qualifying group off strongly. We are looking forward to it."
Sunderland striker Steven Fletcher returns to the Scotland set-up for the first time since March after recovering from a dislocated shoulder.
James Forrest, Chris Burke and James Morrison all pulled out of the squad for the game at Hampden and Tuesday's friendly in Norway, so Gary Mackay-Steven and Craig Conway have been drafted in.
USA qualified for their seventh consecutive World Cup finals after finishing top of the Concacaf qualification group.
Jurgen Klinsmann has named a 23-man squad for the clashes with Scotland and Austria - whom they play next Tuesday - and the Americans' head coach is eager to build some momentum ahead of next year's tournament in Brazil.
"We are excited about the group we have coming in and the big opportunity to finish the year on a high note," said the former Germany striker.
"We want to use these games to prove a point and see that our players are continuing to improve as we build towards the World Cup.
"The results in MLS wound up fitting in with our roster plans, so we didn't need to call in any guys who are still in the play-offs. There are some injuries issues that now give other players the chance to step up."
Donovan, Edgar Castillo, Clarence Goodson and Brad Guzan are unavailable due to injury, but fit-again midfielder Michael Bradley returns and Brek Shea is also recalled.