A fantastic double save in the first half and then a crucial one from Suarez when the Azzurri went down to 10 men saw the Italy captain maintain imperious form.
Was a well-oiled cog in the clockwork that made up the measured defence but could not keep Uruguay at bay for the 90 minutes.
The Juventus man had a great game and did well to keep Cavani out of the game. Will be at the centre of controversy after appearing to fall victim to a bite from Luis Suarez.
M. De Sciglio
Had a quiet game at the back but was on hand to make a perfectly timed tackle when Uruguay were on the counter near the end to spare further blushes for his country.
Barely in the game but went about his business in an assured manner.
Didn't have much of a say in proceedings and was timid on the ball.
The PSG midfielder pulled up with cramp halfway through the second half and had to be taken off in a disappointing performance.
Had a quiet game until his sending off changed the nature and flow of the tie. Deserved his red card after raising his studs to Arevalo Rios' shin.
The evergreen 35-year-old playmaker was not quite at his best but showed his brilliance with dangerous free kicks. It is a shame that this is set to be his last appearance on this stage.
Serie A's top scorer last season created a couple of chances but squandered a great one when he cannoned the ball into the stands after being left unmarked in the box.
The AC Milan hitman was rightly booked for a knee in the back of the head and was targeted by the Uruguayans throughout the first half. Limped off at the break injured and to spare himself the chance of a red card.
Did well to palm away two Pirlo free kicks but did little in the game.
The captain saved his country from elimination with a brilliant bullet header into the bottom corner of the net. Kept Immobile quiet too in an assured performance.
Looked good in the second half but melted away as time wore on. Subbed in the second half.
Looked dangerous getting forward down the flank and linked well with Rodriguez. Didn't have much of an influence on the game.
Slid in to thwart Immobile in the second half with a brilliantly timed interception to stop a goalscoring opportunity.
Didn't do much to make a name for himself in the game. Largely forgotten in the centre of the park.
Booked for a silly foul just seconds after the break and didn't impose himself on the game after that.
Wasted a glorious chance to poke his side in front in the first half after linking well with Suarez. Subbed late on.
Provided some creative output in the South American midfield but was lost in a sea of dark blue shirts for periods .
Was marked out of the game for large periods and was frustrated by his lack of chances. Has had better games for his country.
What can you say about the enigma that is Luis Suarez. The Liverpool striker had a quiet day in front of goal but will surely be punished for his outrageous alleged bite on Chellini minutes before the winner. A disappointment.
Was a real threat down the right-hand side after his introduction in the second half and his crosses created danger in the Italian box.
Came on with time running out but supplied a fantastic left-footed corner for Godin's winner.
Didn't do much after coming on in the second half.