The Nerazzurri have drawn their last two league games, prior to Wednesday's 3-2 Coppa Italia win over Trapani, and their coach will settle for nothing less than another win
The San Siro outfit have not enjoyed such a long run without a league defeat since 2010, when they managed 11 games, and the current spell of good form has lifted them to fourth in the table.
Former Napoli coach Walter Mazzarri has guided his side to a fantastic start to the campaign, having suffered just one defeat in all competitions - though they have drawn their last two Serie A fixtures.
Sunday's result against Sampdoria, which saw Renan Garcia grab a last-gasp leveller for the visitors, prompted Mazzarri to vent his anger, claiming it was the worst Inter performance of the season.
The response from his charges was to produce a 3-2 win in the fourth round of the Coppa Italia against second-tier Trapani on Wednesday.
Goals have been in regular supply for Inter this season, with their 31 strikes in 14 league matches more than any other team has achieved.
That is despite them having just one player - Argentine Rodrigo Palacio with seven - who has scored five league goals or more.
The hosts have a lengthy injury list, with defenders Yuto Nagatomo, Walter Samuel and Cristian Chivu, and attackers Mauro Icardi and Diego Milito set to miss out again.
A calf injury will also keep out midfielder Zdravko Kuzmanovic, while Parma will be hopeful Antonio Cassano features. Aleandro Rosi and Walter Gargano return from suspension.
The visitors have slipped down the table after a run of just one win in five league matches, though the 1-0 win at Napoli last month underlined their threat.
But recent trips to San Siro have held little cheer for the Gialloblu, who have lost the last seven of these fixtures.