Doubts still persist over the fitness of the midfielder, who is unlikely to be risked with the World Cup less than two weeks away
Jorge Sampaoli's side have won all nine games on home soil since November 2012 and will hope to travel to Brazil on the back of another victory in Valparaiso.
Chile won their opening warm-up match against Egypt 3-2 and showed character to come from two goals down to secure victory.
Eduardo Vargas netted twice in the second half for Chile to keep their home record intact but one man not involved was star player Arturo Vidal.
The Juventus midfielder, who has been named in Sampaoli's final 23-man squad, continues to recover from knee surgery and is unlikely to feature in this game to ensure he has the maximum amount of time to recover for Chile's World Cup opener against Australia.
Seven players were cut by Sampaoli after Saturday's win and his finalised squad will get their first outing together in Wednesday's clash.
Northern Ireland come into the game desperate for their first win of 2014. Their latest defeat came against Uruguay on Saturday, which means they have still only won once since August 2011.
Michael O'Neill is using their mini-tour of South America to take a look at some younger players ahead of their European Championship campaign that begins in September and defender Luke McCullough is relishing the chance to add to his debut cap.