Wenger's men need to make history if they are to progress to the next stage of the competition, although the north London side do go into the tie in promising goalscoring form
Sagna, Vermaelen, Koscielny, Gibbs
Walcott, Gervinho, Chamberlain
Abate, Mexes, Silva, Antonini
Nocerino, Van Bommel, Emanuelson
Ibrahimovic, El Shaarawy
Arsene Wenger has several fresh injury worries with Mikel Arteta being taken to hospital with concussion during the Gunners' clash with Liverpool on Saturday and his replacement, Abou Diaby, also suffering a hamstring injury later in the game. Aaron Ramsey is still missing with an ankle niggle and is unlikely to return until next week whilst Yossi Benayoun is also carrying a hamstring problem.
Kieran Gibbs picked up a knock against Liverpool and is a doubt so Carl Jenkinson could replace him at left-back. The growing injuries could lead to Alex Oxlade-Chamberlain or Gervinho starting, while Johan Djourou is in contention for a return to the squad.
Milan boss Massimiliano Allegri is without Alexandre Pato after the forward picking up a thigh injury against Juventus while Clarence Seedorf and Kevin-Prince Boateng have not played since the first leg. Former Gunner Mathieu Flamini has returned to full training but will probably miss out.
Maxi Lopez missed the Italian side's league clash with Palermo on Saturday with Massimo Ambrosini definitely out due to suspension. Urby Emanuelson and Luca Antonini, however, are in line to return.
||DID YOU KNOW?|
- Six of the Gunners' last 19 home wins in Europe have been by four or more goals.
- In their last two home games, Wenger's men netted seven against Blackburn and another five against Tottenham, with Robin van Persie (pictured right) contributing 10 in 11 games across all competitions.
- The north London outfit have managed 55 goals in 27 league games this campaign, two more than they recorded at this same stage of the 'Invincibles' season of 2003/04.
- AC Milan have been knocked out at this stage of the Champions League in each of the last four seasons.
- In their last league game, the Italian giants destroyed Palermo by the same scoreline they beat Arsenal by in the first-leg (4-0) with Zlatan Ibrahimovic netting a hat-trick.
- Milan went into the 2003/04 quarter-finals with a 4-1 lead over Deportivo La Coruna, only to crash out after loosing 4-0 to the Spanish side in the second-leg.
- However, no-one has ever managed to overturn a foul-goal deficit over two-legs in the Champions League.