Following his fine performance for Dortmund on Friday, Mario Gotze is expected to start in the playmaker role, deputising for the omitted Mesut Ozil. Sami Khedira also has been excluded from Joachim Low's squad, meaning that Toni Kroos will most likely start in central midfield. The back four is still yet to be decided, but Philipp Lahm is expected to be picked on the left, meaning that Christian Trasch will play in the right-back position.
Cesar; Maicon, T. Silva, Lucio, A. Santos; Ramires, Elias; Robinho, Ganso, Neymar; Pato
Mano Menezes is yet to hold a training session ahead of the game, and whether he will make changes to his Copa America team is in question. David Luiz and Lucas Leiva have been omitted from the coach's squad; Elias is expected to deputise for the central midfielder, while regular starters Lucio and Thiago Silva will feature in central defence.
DID YOU KNOW?
Germany have won all seven of their Euro 2012 qualifiers, and eight of their 12 matches since the 2010 World Cup.
Stuttgart striker Cacau has the opportunity to face the national team of his homeland for the first time on Wednesday.
The DFB youngsters beat Brazil 4-3 in the U17 World Cup third place match earlier this summer.
Brazil have won their last two matches against Germany: 3-2 in the 2005 Confederations Cup, and 2-0 in the 2002 World Cup final.
After contemplating a career with Germany, Bayern Munich's Luiz Gustavo has a chance to earn his first cap for Brazil on Wednesday.
Selecao have won six out of their 12 matches since Mano Menezes took over as coach in the summer of 2010.
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The 19-year old had an outstanding performance in his Bundesliga opener on Friday, and is expected to earn a starting role in place of Mesut Ozil. Hailed by Matthias Sammer as one of the best talents Germany have ever produced, all eyes will be on the Dortmund man.
Brazil's 19-year old jewel has already established himself in Menezes' squad, and shown flourishes of brilliance for country. After a disappointing Copa, and opposite another highly-rated attacker, he will have heavy expectations on his shoulders.
Brazil struggled at the Copa America and quite clearly are in the midst of an identity crisis, but Germany are without a number of stars, and recently have had trouble in their more high-profile friendlies. The DFB squad usually score first and concede late; a draw in Stuttgart appears the most likely end result.