The Germany international is reportedly considering his options after the arrival of Pep Guardiola at the Allianz Arena saw his playing time cut this season.
However, his representantive says that the 24-year-old will not be plying his trade for the Catalan giants next season.
"Barcelona is definitely not an option for Thomas," Lodwig Kogl told Bild.
Muller has scored 25 goals in all competitions this season but has found it hard to come by a regular spot in the team of late.
The likes of Liverpool, Manchester United and Arsenal have also been linked with a summer move for his services this summer.