Olympique de Marseille striker Dede Ayew believes the Black Stars stand the best chance of qualifying since they beat Flames 2-0 in the first leg
Ghana won the first leg 2-0 in Accra and will need a draw of any kind to qualify for the final of the tournament to be held in South Africa.
Speaking to Goal.com Kenya on Wednesday after training at Moi Kasarani, Ayew remained optimistic that they stand a better chance of making it to the final of the Africa showpiece.
"We have the best chance to qualify and will not take Malawi for granted. We are in a confident mood going into the match and am very sure we will be in South Africa come 2013."
The Black Stars have pitched camp in Kenya in preparations for the decisive match and are due to depart for Malawi on Friday morning.
"We have a better advantage going into the match having won 2-0 in the first leg. We will need to protect that cushion and also attack for the killer goal...we have a good opportunity of advancing. What is required from us is to remain focused and not lose our heads in such a crucial decider."
Ayew singled out hosts South Africa, Cameroon and Morocco as some of the nations that will pose big threat in the 2013 final.
Ghana coach Kwesi Appiah confirmed that Juventus star Kwado Asamoah was doubtful for the match. "We have a problem with Asamoah (Kwado). He has an ankle injury and has not trained today (Wednesday) but doctors are monitoring his progress and hopefully he will be available. If he doesn't, then we will use the other players we have in the squad."
Malawi tactician Kinnah Phiri has recalled veteran striker Esau Kanyenda and Chiukepo Msowoya who missed the first leg match in Accra to beef up his striking force.