Real Madrid's recent form - including back-to-back wins over Barcelona - will be a concern to Sir Alex Ferguson but the home side have been relentless in recent weeks, having won their last 10 games at Old Trafford, scoring at least two goals in nine of those games.
Robin van Persie will feel he should have given United a first leg advantage three weeks ago, with several chances passing the Netherlands by the last time these two teams met.
William Hill have enhanced the Van Persie wincast from 12/5 (3.40) to 4/1 (5.0) which makes it a lot of attractive proposition to punters who believe the Premier League's second highest scorer can power his side to win in front of the their home support.
Shinji Kagawa scored three times in United's 4-0 win over Norwich at the weekend and his wincast price has been boosted to 11/1 (12.0).
Real Madrid's main goal threat should come from Cristiano Ronaldo who has been in a rich vein of form for Jose Mourinho's side in recent weeks.
Rested for Saturday's Clasico match, the 28-year-old struck twice at Camp Nou in the Copa del Rey meeting exactly a week ago and scored the equaliser in the first leg.
The Ronaldo wincast was previously 7/5 (2.40) but has been enhanced by William Hill to a much more enticing 5/2 (3.50) which will be music to the ears of those who believe the Spanish side will be able to overcome Manchester United.
|Robin van Persie to score and Manchester United to win at 4/1 (5.0)
||Real Madrid to win and Cristiano Ronaldo to score at 5/2 (3.50) with William Hill|
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Jim Knight is Betting Editor at Goal.com and has been tipping football games since he was old enough to place a bet. He is a Leicester City fan, writer and member of the We Are Going Up Podcast
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