The Ballon d'Or holder has lavished praise on "Germany's undisputed star" and the Netherlands duo.
Ozil and Messi clashed many times during the former's time at Real Madrid, while Robben helped the Bavarian outfit thrash the Catalans 7-0 on aggregate in last season's Champions League.
Van Persie, meanwhile, was part of the Arsenal side that sprung a surprise comeback on the Blaugrana in February 2011 and the 26-year-old Argentine is full of praise for all three players.
"Robin van Persie, Arjen Robben and Mesut Ozil are great players. Ozil is Germany's undisputed star. He's top class and incredibly creative," the Ballon d'Or holder told De Telegraaf. "Van Persie is a very complete player. He is an all-round attacker who can score loads of goals. Robben is a class act as well, but a different type of player.
"He's very unpredictable. He's very quick with his dribbles and can leave several players behind him with one acceleration."