The world champions' coach has admitted that a number of the youngsters that started the 4-2 friendly loss to the Albiceleste will not feature against Scotland on Sunday
The coach picked a young lineup for the re-run of July's World Cup final, which Mario Gotze decided in the Europeans' favor with his dramatic extra-time strike.
However, Germany was ripped asunder by Di Maria, who scored one goal and created three others as the Albiceleste gave Low plenty of food for thought ahead of Sunday's Euro 2016 qualification opener against Scotland in Dortmund.
"We made some mistakes in our defense but I can't really blame the team because the squad has never played together like this," the world champions' coach told reporters. "Sometime you have to accept it.
MORE: Alex Morgan upset at 159-degree temps | Transfer photos
"We played pretty well during the first half and created three or four great chances. But we did not convert them.
"Some of our players are not in their best shape and others are injured. We have to classify this match and Sunday is what counts.
"But we have to think about this match and I think tomorrow [Thursday] we will add some players to the squad because it was obvious how some players had problems tonight.
"Plus, I don't think [defender] Mats Hummels will be totally fit for Scotland."
Low insisted, though, that he always thought that he would have to deal with the effects of a World Cup hangover.
"I expect some difficulties during the next six months," he mused. "It is never easy after a huge success to be ready again soon.
"We have many players who are injured or have been injured for a long time. Also, we are the world champions now and everybody is hunting us."