The Bundesliga giant suffered from a spate of injuries throughout the first half of the season and currently sits 12 points adrift of Bayern Munich, having played a game more.
Saturday's loss was the third home defeat in the league on the bounce and Klopp is looking forward to being able to recuperate after a spectacular loss of form.
"Something which started very well has ended quite miserably. And that's the way if feels like now," he told Sky Deutschland. "We're in need of the break. But it's us who are responsible and we must think about some things."
Reflecting on the match, Klopp said that his side failed to rise to the occasion after Sami Allagui's goal, which gave Hertha the lead on the stroke of halftime.
"The reaction to the second goal was not good, it must be said," the 46-year-old added. "We let Hertha come back completely unnecessarily."