The three Bayern stars, as well as Dortmund's Marcel Schmelzer, have been ruled out for the friendly against the Oranje, while Roman Neustadter is happy about his first call-up.
Die Roten have announced that both the experienced midfielder and the young playmaker are suffering from infections, which will keep them from taking part in the friendly match in Amsterdam. The German FA (DFB)'s official website, meanwhile, has confirmed that Boateng picked up a hamstring injury against Eintracht Frankfurt on Saturday, while Schmelzer has a bruised ankle.
Elsewhere, Schalke defensive midfielder Roman Neustadter has expressed his delight at being called up by national team coach Joachim Low for the first time.
"At first I was shocked, because I didn't expect it," the 24-year-old explained to Bundesliga.de. "Of course I was extremely delighted and could not find words for the joy I felt. "[Low] said that I deserve it due to my performance, he now would like to get to know me and that he is looking forward to Monday."
Germany and Netherlands face off in Amsterdam on Wednesday in a high-profile friendly and a rematch of their meeting in the Euro 2012 group stage.