The 37-year-old Dutchman has told his Bianconeri counterpart to accept the fact that a busy schedule is a consequence of success.
The Bianconeri boss had expressed his unhappiness at having to face the Rossoneri so soon after Thursday's Europa League last-32 second-leg clash with Trabzonspor, which the Old Lady won thanks to goals from Arturo Vidal and Pablo Daniel Osvaldo.
Speaking ahead of Sunday's Serie A clash at the Giuseppe Meazza, Seedorf was quick to point out that Conte should by now be well aware of the consequences of competing on two fronts.
"Conte knows that the big teams have to deal with the calendar and that they will have two games only a couple of days apart," the 37-year-old Dutchman told Tuttosport. "Anyone who plays in Europe knows that this is the nature of the calendar. You do not complain about it.
"Conte has done a great job, I congratulate him. Ever since they won the league title, they have grown. When you win, you automatically improve morale, acquire respect. Conte, like [Fiorentina boss Vincenzo] Montella, has revamped the Italian football and I think it's a good thing. These are two coaches who bring freshness."
Milan has endured a difficult season and currently sits in ninth, though the club has improved since Seedorf's appointment in January, having suffered only one league defeat in the last five outings.
"I do not look at the standings," the former Rossoneri and Real Madrid midfielder mused. "I want another great performance against a great team. For us, this is the only thing that counts.
"I've won two Champions League finals against Juventus [for Madrid in 1998 and Milan in 2003]. I scored against Juventus for three different clubs. But that is history. And this game does not define my coaching career, but it might make a difference to Milan's season."