The Dutchman defended his lineup after an embarrassing 4-0 defeat to League One opposition, and called on the club's concerned followers to keep the faith.
The Red Devils were routed 4-0 by their League Two opponents, with Will Grigg and Arsenal loanee Benik Afobe each bagging a double on a sorry night for the visitors' Dutch coach, who remains without a win after his first three games in the hotseat.
However, Van Gaal made no apologies for the embarrassing loss, defiantly insisting that he was right to pick a team full of youngsters and fringe players.
"I have no regrets," he told Sky Sports. "We have to analyse the problem and you have to change your methods. We have done that and I think our methods were good. But also it was risky to play one against one; therefore Milton Keynes could score.
"When you see the goals against us, I believe there were big errors of our own situations. We cannot make these errors. It is very difficult to come back from 2-0. [In the] second half we created chances but didn't have luck to score – but we created a lot of chances."
Indeed, Van Gaal called on the club's concerned supporters to keep the faith, arguing that he needs time and patience to turn the club around.
"[Fans need] to believe in our philosophy," he argued. "We are building a team that you cannot make in one month and not in one year.
"It's very disappointing but I hope they shall maintain their confidence in the club and in our philosophy because that philosophy takes time."