The controversial striker is set for another spell in Serie A, while the Algeria international will continue his career in England
Inter is close to agreeing a deal with Southampton to sign Dani Osvaldo on loan which would send midfielder Saphir Taider in the opposite direction.
The Serie A side hopes to soon agree personal terms with the Italy striker, who made only 13 league appearances for the Saints last season before being loaned to Juventus less than six months after joining them from Roma for a club-record 15 million euro fee plus add-ons.
The 28-year-old Osvaldo previously wore the jerseys of Huracan, Atalanta, Lecce, Fiorentina, Bologna and Espanyol.
Taider, a box-to-box central midfielder who can also play out wide, was part of the Algeria squad that made it to the round of 16 at the World Cup finals, making two appearances in Brazil.
The midfielder, 22, only joined Inter from Bologna in the summer of 2013, but failed to live up to the high expectations at the Giuseppe Meazza side.
MORE: Full Goal 50 list | Beautiful people in Brazil
The arrival of Yann M'Vila on loan from Rubin Kazan has damaged Taider's hopes of holding down a place in Walter Mazzarri's first team, with Cardiff's Gary Medel also linked with Inter and he is now set to continue his career in the Premier League.
Southampton is also willing to take 34-year-old Argentina defender Hugo Campagnaro as part of any deal.
New Southampton boss Ronald Koeman is eager to bolster his squad following the departures of five key players this summer and with Morgan Schneiderlin prepared to hand in a transfer request to force a move to Tottenham.
Schneiderlin and Jay Rodriguez are wanted by Spurs but Saints insist they will not sanction their sales having already lost Rickie Lambert, Luke Shaw, Adam Lallana, Dejan Lovren and Calum Chambers.
Those departures have brought in more than €110m in transfer fees, with Dusan Tadic and Graziano Pelle the only incoming signings so far at a combined cost of around €25m.