Roy Hodgson & Co. have landed in Brazil ahead of their tournament opener against Italy on Saturday, but the Honduras and Wigan midfielder feels the humidity will be a concern.
The Three Lions are set to kick off their Group D campaign against four-time champion Italy in Manaus – a location known for its humid conditions – on June 15.
Wigan midfielder Espinoza has singled out England as one of the countries which may struggle to cope in South America after it played out a goalless draw with Honduras on Saturday in Miami.
"I think [the climate] will be a big factor for England. England players are not used to it," Espinoza is quoted as saying by the Daily Mirror.
"I remember where I lived in Manchester, going to Wigan, the sun came out, but it's an artificial sun. We would come here to the [United] States in preseason with Wigan and you can tell how tough it is for the English players, Scottish and Irish guys, too, to come on this side of the world."
"Not many places will be as hot in Brazil, apart from Manaus," he contnued. "If they keep the ball like they did against us, they will not get tired. They have the players to keep the ball. That will keep them fresh, stop them getting tired. They're young guys, too.
"But it will be dangerous for them if they don't keep the ball because it is going to be hot."