Manuel Pellegrini's men would be crowned champions should they avoid defeat to West Ham, while Manchester United could still sneak a Europa League spot ahead of TottenhamAt 21.39BST on April 16 it did not seem possible. Manchester City had just been held to a 2-2 draw by then-bottom club Sunderland and it looked for all the world like Liverpool was going to march on and collect its first Premier League title in 24 years.
Samir Nasri's strike two minutes from time, a goal that could, in the end, make all the difference for City, rescued a point against the Black Cats after two goals from Connor Wickham but, with the Merseysiders in imperious form, there only appeared one outcome; Liverpool was going to be the champion.
How things can change. A quite remarkable collapse from Brendan Rodgers's side, where it picked up just one point from two games against Chelsea and Crystal Palace, saw the title dramatically slip from its grasp.
City, meanwhile, held its nerve to record four wins on the spin and knows that just a point in its final game of the season against West Ham would, should Liverpool fail to put 13 past Newcastle, see it crowned champion.
With the Champions League places decided after Everton's defeat to Manuel Pellegrini's men - which ensured that Arsenal will finish fourth - attention turns to the Europa League spots and the battle to finish sixth.
Manchester United's dismal campaign comes to an end at Southampton on Sunday in what is set to be Ryan Giggs's final game in charge before Louis van Gaal takes control after his World Cup commitments with Netherlands.
The Red Devils could sneak into Europe's secondary competition should Tottenham, which currently has a three-point cushion over United but a far inferior goal difference, suffer defeat to Aston Villa and Giggs leads his side to victory at St Mary's Stadium.
Elsewhere in the table, Crystal Palace and Sunderland could cap what has been an extraordinary end to the season for both sides by finishing 10th and 12th, respectively.
Tony Pulis, who has been nothing short of a revelation since replacing Ian Holloway at Selhurst Park back in November, has lifted the Eagles from the bottom three to 11th and could still finish above former side Stoke City in the table.
Sunderland, meanwhile, has pulled off something of a great escape with the Black Cats capable of finishing as high as 12th in the table, having been rock bottom just two weeks previously, should they come out on top against Swansea City on Sunday and West Ham falls to defeat at Manchester City.
As for the fight to avoid the drop, both Cardiff City and Fulham have already had their fate confirmed and Norwich City is set to join them in the Championship.
The Canaries, who secured what normally would have been a commendable point against Chelsea at Stamford Bridge last time out, will drop down a division unless they defeat Arsenal and West Brom loses to Stoke, overturning a 17-goal deficit in the process.