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The U.S. international had his fourth major knee operation in a three-year span after suffering another injury during a match with Bolton's Under-21 squad.

Just when it seemed Stuart Holden's injury luck couldn't get any worse, the U.S. international suffered another devastating blow.

Holden will be sidelined for six to nine months after undergoing surgery on ligaments in his right knee, Bolton Wanderers announced Tuesday. It's the fourth major knee operation in a three-year span for the 28-year-old, who suffered the injury last week while playing for Bolton's Under-21 squad — his first game back following a torn ACL in July.

The midfielder, who came back from a broken leg in March 2010 to make one appearance for the USA at the 2010 World Cup, underwent surgery on his left knee in March 2011 following an ugly tackle from Manchester United's Jonny Evans. Holden then suffered a setback that September.

Holden returned to the national team this past summer, earning eight caps before suffering a torn ACL in his right knee during the Gold Cup final against Panama.

The player responded to Bolton's announcement on Twitter, turning attention to his recent engagement and vowing to continue his soccer career.

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