Manchester United had hoped to put its depressing domestic struggles behind it by maintaing its impressive Champions League form against Olympiakos on Tuesday.
However, the Greeks piled more misery on David Moyes' men by recording a deserved 2-0 victory over the Premier League holders in Athens.
Goal selects the best imagery from United's latest setback since the departure of Sir Alex Ferguson, as well as Borussia Dortmund's rousing 4-2 victory over Zenit in Russia.
Dortmund's Henrikh Mkhitaryan finds the net just four minutes in, after good work from Marco Reus.
One minute after the opener, Reus fires home to make it 2-0 to the Germans.
Zenit boss Luciano Spalletti is left bewildered by his side's sluggish start.
Robert Lewandowski restores Dortmund's two-goal advantage, after Oleg Shatov had struck for Zenit.
In the 70th minute, Zenit is awarded a penalty after Fayzulin is upended by Piszczek; Hulk converts.
Lewandowski adds his second, though, to earn Dortmund a 4-2 win, to Jurgen Klopp's delight.
The devoted Borussia Dortmund fans who made the trip to Saint Petersburg go home happy.
In a sea of red and white, Manchester United lined up against Olympiakos at Karaiskaki Stadium.
A goal out of the blue from Alejandro Dominguez caught United offguard in the 38th minute.
It was Giannis Maniatis who saw his shot flicked past David de Gea by Dominguez.
Sucker punch: Manchester United is hit hard just before halftime
Things go from bad to worse in the second half as David de Gea is found once again grasping at thin air.
Arsenal loanee Joel Campbell nutmegged Michael Carrick before curling the ball into the corner.
Wild celebrations follow as Campbell is mobbed by teammateas after making it 2-0 to the Greeks.
Wayne Rooney and Co. face an uphill struggle in the return leg at Old Trafford.