The former Manchester United first-team coach rejected the Londoners' initial offer but the club persisted and Meulensteen has accepted a deal in which he will run the coaching.
The Dutchman rejected an initial offer from the Londoners last month.
However, Fulham did not give up hope of enticing the former Manchester United first-team coach as the club pressed ahead with plans to shake up its backroom setup. He also had a lucrative offer on the table from the Qatar FA but turned that down to give the Cottagers fresh hope that he could be persuaded to move to west London.
Fulham made a second move for Meulensteen and, amid interest from Crystal Palace in appointing him their new manager, a deal was agreed. The new role of head coach has been created at Fulham for Meulensteen, who is described by Sir Alex in his new autobiography as a “magnificent coach” and who is rated by Robin van Persie as "one of the best in the world".
“Fulham is delighted to announce the appointment of Rene Meulensteen as head coach,” the club said in a statement on Wednesday afternoon. “Meulensteen joins the club with immediate effect working alongside manager Martin Jol”.
Jol is believed to have been fully behind plans to lure fellow Dutchman Meulensteen after accepting that the first-team coaching needed freshening up.
Fulham has started the season with a wretched run of results that leaves the club in the relegation zone, with 10 points from 11 Premier League games.