The Frenchman was withdrawn after 37 minutes of Saturday's 4-1 home victory following a clash of heads with Alexander Tettey, appearing dazed in the moments before he left the field. Wenger admitted that the midfielder could miss the Gunners' Champions League clash against Borussia Dortmund on Tuesday.
"He had [a] concussion," Wenger said. "He had double vision, so on the advice of the doctor I took him off, because I did not want to take any gamble.
"I don't know if he'll be available for Dortmund, it depends now what the doctors will decide. Sometimes they are not allowed to play for five days, it depends how big the concussion was."
His absence would represent a significant setback for Arsenal, with the midfielder having impressed since returning to the club from Milan.
Flamini's form has been one of many bright spots in what has been an excellent start to the campaign for the London club, which is two points clear at the top of the Premier League and unbeaten since the opening day of the season.