Carlos Tevez was this week handed a six-month disqualification, a 1,000 pound fine and ordered to carry out 250 hours community service after pleading guilty to driving while disqualified and without insurance.
The following day, his teammate Samir Nasri also received a six-month ban and picked up a 2,100 pound fine for exceeding the speed limit three times in 2011.
However, when asked if these events might have a negative impact on his squad, Mancini replied: "I don't think this. This is their private life.
"We can do nothing about this. This can happen sometimes."
And specifically discussing the case of Tevez, the Italian added: "I didn't speak with him about this. I think that Carlos made a mistake and he will pay for this. But usually he has good behavior."
City faces local rival Manchester United in its next game, traveling to Old Trafford on Monday evening.