The former Manchester City manager has had his contract at Loftus Road terminated after the club recorded the joint-worst start in a Premier League season.
QPR has sacked Mark Hughes after a run of 12 games without a win this season has left the club bottom of the Premier League.
Defeat at home to relegation rivals Southampton last weekend confirmed the R’s joint-worst start to a Premier League season – equal to Everton’s 1994-95 opening - with a section of supporters holding banners calling for the appointment of former Tottenham boss Harry Redknapp.
Assistant manager Mark Bowen and first-team coach Eddie Niedzwiecki will take charge of the team’s trip to face Manchester United on Saturday.
"This decision has been taken after careful consideration by the Board of Directors, following numerous meetings over the last few days," a statement on the club’s official website read. "The Board of Directors wish to thank Mark for his commitment, hard work and dedication in his ten months in charge.
"Mark has shown integrity and professionalism throughout his time here, but ultimately the circumstances we find ourselves in have left the Board of Directors with very little choice but to make a change. The Board will now be working actively to put a new managerial structure in place as soon as possible.
"Mark Bowen and Eddie Niedzwiecki will take charge of the R's trip to Manchester United in the Barclays Premier League on Saturday afternoon."
Redknapp is the early favorite to fill the managerial vacancy, with the former Portsmouth boss also interesting Ukraine.
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