Van Persie has been the quicker off the mark, scoring eight goals so far this season in all competitions; however, the 29-year-old stressed that his relationship with Rooney has been critical in the early stages of the season and is only getting better.
"Things are going well and our understanding is getting better all the time," Van Persie told Manchester United TV. "Everyone could see from Day 1 that we were working well together. We like to play together and we help each other.
"Sometimes Wayne plays at the top, sometimes I do and then he drops in and then you have Danny [Welbeck] coming in from the left sometimes too. I might also go out there for a few minutes in a game or Wazza [Rooney] does. I think it's only the second or third time that we've played in this formation, but the main thing is we've had a good game and got three points."
Rooney scored his first club goals of the season on Saturday against Stoke City, where he made up for his early own goal by netting twice to add to strikes from Welbeck and Van Persie. The Dutchman is impressed with Manchester United's attack as a whole, insisting that they are creating chances from different positions.
"We can score from any angle," Van Persie said. "The first one against Stoke was from a cross from the left and a good header, the second was from a low cross, the third came from a cross again from the opposite side [to the first] and then the fourth goal came from a corner, so we've scored all sorts of different goals. In previous games as well we've shown we can score from every sort of angle which is a good sign and a good weapon for us."