Gary Cahill is handed his Chelsea debut in place of the injured John Terry and fit-again midfielder Michael Essien makes his first start of the season with Lampard still out.
Bosingwa replaces the suspended Ashley Cole, while Fernando Torres and Daniel Sturridge are chosen up front.
Chelsea: Cech; Ivanovic, Cahill, David Luiz, Bosingwa; Essien, Meireles, Malouda; Sturridge, Torres, Mata.
Subs: Turnbull, Ferreira, Bertrand, Hutchinson, Romeu, Piazon, Lukaku.
Manchester United: De Gea; Rafael, Evans, Ferdinand, Evra; Valencia, Carrick, Giggs, Young; Rooney, Welbeck.
Subs: Amos, Berbatov, Park, Hernandez, Fabio, Scholes, Pogba.
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