The Colombian is unlikely to be on the plane to Brazil this summer, but insists he will fight to make a dramatic recovery.
Monaco striker Radamel Falcao has not given up hope of featuring at the World Cup despite suffering a serious knee injury.
The Colombia international was carried from the field on a stretcher during the Ligue 1 club's 3-0 triumph over Monts d'Or Azergues in the Coupe de France on Wednesday.
Monaco confirmed on Thursday that the club's record signing will undergo surgery after scans revealed he had damaged the anterior cruciate ligament in his left knee.
The 27-year-old's hopes of playing at the World Cup in Brazil later this year would appear to be over, but Falcao is retaining hope of appearing at the tournament.
"I want to thank all of you for your messages in the last hours," he wrote on Twitter.
"I have been touched by all the support and love of all the people around the world.
"I am not going to hide that I am very sad. My heart is destroyed. But I have faith (that I am) holding right now to keep my dream alive to be at the World Cup.
"God makes the impossible possible. I believe in Him."