The combative midfielder is continually being linked with a move to a bigger league, but his current club stressed that he's not for sale
The midfielder has long been linked with a move to Manchester United, while Napoli also made an enquiry for the 23-year-old this summer.
However, the English champions have turned their attentions to Thiago Alcantara instead, while a move to the San Paolo now seems out of the question as well following Brands' latest comments.
"We do not want to lose Strootman this summer. He knows that he will stay at PSV for another season," Brands told De Telegraaf.
Strootman is a product of the Sparta youth academy and also wore the Utrecht jersey before joining PSV in the summer of 2011. He has since developed into a key player at the Eindhoven side.
The midfielder's contract with PSV runs until June 2016.
The Eredivisie side previously lost Jeremain Lens to Dynamo Kiev, Dries Martens to Napoli and Erik Pieters to Stoke City, while Ola Toivonen is in talks with Norwich City.