The Uruguayan admits he is relishing the chance of a more central position in the Swede's absence as PSG prepares to travel to face Chelsea.
The Swedish frontman picked up a hamstring strain in the first leg of the Champions League quarterfinal clash between the sides, which PSG won 3-1 at home, ruling him out of Tuesday's second leg at Stamford Bridge.
Yet Cavani, who scored against Reims at the weekend in Ibrahimovic's absence, is sure he can shine in a more central attacking role.
"I am better in the axis," the Uruguayan told L'Equipe. "This is normal; this is my job. It's a great responsibility for me."
Les Parisiens won the opening encounter at Parc des Princes and Lucas Moura, who came on in place of Ibrahimovic last Wednesday, says the Ligue 1 leaders have a duty to progress.
"We have a great advantage," the Brazilian said. "We will be very focused. It will be hard but we can do it. We have a responsibility to finish the job."