Both keepers have been key parts of their respective national teams for a number of years and clash on Monday in a friendly at Craven Cottage.
Enyeama is delighted to be playing against such opposition but believes he and the Juventus skipper are from "different worlds".
"I am happy that we are playing a high-profile friendly against Italy. We have an opportunity to play against a renowned country and former world and European champions, he told Goal. "There is no battle between me and Buffon because we are in two different worlds. He is a good goalkeeper, no doubt about that, but it would be an unnecessary distraction comparing me with the Italian goalkeeper.
"I expect an exciting match but the battle is beyond two individuals."
Italy and Nigeria kick off in west London at 2:45 p.m. Eastern.