The Spurs goalkeeper was not risked for Sunday's 1-0 Premier League defeat to Newcastle on advice from club medics but is set to be ready for his country's World Cup playoff.
The goalkeeper suffered concussion in Spurs' 0-0 draw with Everton on Nov. 3 and did not feature in the victory over Sheriff on Thursday or Sunday's defeat to Newcastle. However, his manager insists that it was simply a precaution not to play Lloris against the Magpies and believes that the goalkeeper will be available for selection for Friday's first-leg meeting between les Bleus and Ukraine.
"The medical department felt it was probably a bit too soon. I expect he will be able to play for France," Villas-Boas told reporters.
The decision not to remove Lloris from the Everton game after his collision with Romelu Lukaku drew criticism from some quarters, but the Tottenham manager maintains that the club was correct in its actions.
Asked whether the decision was right, he replied: "Yes, completely, 100 percent," before adding that further medical tests had prompted the Frenchman's withdrawal from Sunday's match.
"It's a test they do, which they value a lot, called an impact test, so I had to stick to what they said," Villas-Boas continued. "Nothing has come to light; he is absolutely fine. The medical department advised us not to use the player. We followed rules. We did everything by the book. The medical department that saved the life of a player [Fabrice Muamba, who suffered a cardiac arrest during Tottenham's FA Cup tie with Bolton in 2012] deserves respect."