The Chelsea center back left the field at Wembley after colliding with keeper Joe Hart following a push from Belgium’s Dries Mertens in the Three Lions 1-0 victory on Saturday.
"Gutted to hear Gaz is ruled out," Lescott said on his Twitter account.
Cahill suffered a double fracture of his jaw after having an x-ray following the game and was consequently ruled out of the tournament, becoming the fourth player from Roy Hodgson’s squad to have to pull out of the competition.
Lescott replaced the former Bolton man after 19 minutes and helped England record its second clean sheet under the tenure of its new manager and now looks in prime position to partner John Terry in the heart the defense against France on June 11.
The Manchester City defender believes Mertens should have been punished more severely than the yellow card he received.
"The challenge that caused it was more reckless and dangerous than most two-footed tackles so why only yellow?" Lescott tweeted.