The runaway leader had the chance to seal the title last week against Besiktas, but a 1-1 draw ensured the club would have to put its celebrations on ice.
However, the triumph has now been secured after a 0-0 stalemate at Sukru Saracoglu stadium, ensuring a 19th Turkish title for the club and a first for head coach Ersun Yanal.
City rival Galatasaray had dominated the Super Lig for the last two seasons, but has fallen away this term thanks to some poor early-season form, which eventually led to a change in coaching.
Roberto Mancini's men suffered a shock 4-0 loss at home to Kasimpasa to leave Yanal's men on the brink of glory, with the draw against Besiktas only delaying the celebrations by a week.
Besiktas is third in the standings, a point behind Galatasaray.